Two women were killed and eight others injured, when a luxury bus rammed into their jeep at Gotheghar Bridge in the district, police said.
The mishap occurred on the Mumbai-Nashik highway when the bus, carrying members of a marriage party, was heading to Mumbai from Jalgaon, said Mahesh Shete, inspector, Shahapur police station.
The jeep, which was also ferrying members of another marriage party, was heading to Ulhasnagar from Mokhada, the officer said.
The deceased have been identified as Pramila Patil (40) and Mayuri Darade (32).
Nobody from the luxury bus was injured, he said.
A case has been registered and a probe was underway, Shete said.